Peptide Pen - Mito Repair (SS31)

Product Name: Mito Repair Pen 

Formulation: 2.6 mL pre-filled pen 

Clicks per Pen: 240 

Total Amount: 50 mg SS–31 

Supplied with: 6 sterile needles (extras available) 

Description 

SS–31 (also known as Elamipretide or Bendavia) is a synthetic tetrapeptide with the sequence D-Arg-Dmt-Lys-Phe-NH2 (where Dmt = 2,6‘-dimethyltyrosine). It is a mitochondria-targeted, cell-permeable peptide designed to concentrate in the inner mitochondrial membrane. 

Mechanism of Action 

SS-31 selectively binds to cardiolipin, a unique anionic phospholipid almost exclusively found in the inner mitochondrial membrane. This interaction: 

• Stabilizes cardiolipin structure and prevents peroxidation by reactive oxygen species (ROS) 
• Protects electron transport chain complexes (especially Complexes I, III, and IV) from oxidative damage 
• Reduces mitochondrial ROS production and cytochrome c release 
• Preserves mitochondrial membrane potential (Am) and cristae architecture 
• Inhibits opening of the mitochondrial permeability transition pore (mPTP) 
• Improves ATP synthesis efficiency and mitochondrial bioenergetics 

By concentrating >1,000-fold in mitochondria (due to its cationic nature and aromatic residues), SS–31 exerts potent localized antioxidant and protective effects without significantly affecting cytosolic redox state. 

Indications & Usage 

Mito Repair (SS-31) is used to support mitochondrial function and cellular resilience under oxidative stress. It is indicated for: 

• Protection and restoration of mitochondrial bioenergetics 
• Support for recovery from metabolic, ischemic, or oxidative stress in tissues 
• Assistance in age-related or disease-associated mitochondrial dysfunction 
• General cellular energy, endurance, and tissue repair support 

Contraindications & Warnings 

Do not use if you have: 

• Known hypersensitivity to SS–31 or any excipient 
• Active malignancy (theoretical concern regarding cellular metabolism enhancement) Severe uncontrolled hepatic or renal impairment 
• Pregnancy or breastfeeding 
• Age under 18 years 

Warnings 

• Use only under medical supervision with periodic monitoring (e.g., clinical symptoms, metabolic parameters). 
• Not a substitute for standard medical treatment of mitochondrial disorders, ischemia, or chronic diseases. 
• Discontinue immediately and seek medical attention if severe symptoms occur (e.g., severe fatigue, chest pain, shortness of breath, or signs of allergic reaction). 

Dosage & Administration 

• Subcutaneous injection only. 
• Standard Dose: 5 mg (22 clicks) per injection 
• (delivers exactly 5 mg based on pen calibration) 
• Alternative Lower Dose: 3 mg (13 clicks)– for longevity/maintenance or sensitive protocols 
• Frequency: 2-3 times per week (e.g., Monday/Wednesday/Friday, or spaced around training/recovery days) 
• Timing: Morning or pre-activity to maximize energy, stamina, and recovery support 
• Cycle: Typically, 4-12 weeks on, followed by 4 weeks off to maintain efficacy
• Optional Loading Phase: First 2-4 weeks: 5 mg 3x/week, then reduce to 2x/week or once weekly for maintenance 

Administration Instructions

1. Wash hands and prepare a clean surface. 
2. Attach a sterile needle. 
3. Dial the required number of clicks (e.g., 22 clicks = 5 mg). 
4. Clean injection site (abdomen or thigh) with alcohol swab.
5. Insert needle at 45-90° angle and inject slowly. 
6. Withdraw needle, dispose safely, and cap the pen. 
7. Rotate injection sites to minimize irritation. 
8. Always inspect solution before use: Do not inject if cloudy, discoloured, or containing particles. 

Side Effects 

SS-31 is generally well tolerated across clinical and preclinical studies. Reported reactions are uncommon and usually mild/transient, including: 

• Mild injection-site irritation, redness, or itching 
• Transient headache or light-headedness 
• Temporary fatigue or changes in energy levels during initial use 
• Rare mild gastrointestinal discomfort 
• If any severe or persistent symptoms occur (e.g., severe headache, chest pain, or allergic signs), discontinue use and contact your healthcare provider immediately. 

Storage & Handling 

• Store either in refrigerator (fridge); never freeze or in a cool dry place (≤25-30°C / 77-86°F). Keep pen capped and protected from light and heat. 
• After first use: Same storage conditions. 
• Keep out of reach of children. 
• Discard if expired or solution appears abnormal. 

Powered by Precision MSSPT 

Peptide Pen formulations set the standard for research peptide delivery in challenging environments. Powered by exclusive MSSPT, each pen combines buffers, antioxidants, and proprietary agents in a compact, user-friendly injector delivering strict control over pH, light, oxygen, oxidative factors, and moisture even under South Africa’s subtropical variability or the UAE’s extreme desert heat and humidity. This proprietary technology positions Peptide Pen as the premier choice for researchers in these regions: no mixing, no guesswork, and reliable, high-fidelity results despite demanding protocols and climates. Every Peptide Pen is built for exceptional durability, reliability, and performance, providing precision molecular stabilization in every dose, wherever your research takes you. 

IMPORTANT NOTICE 

This product is not intended to diagnose, treat, cure, or prevent any disease. Statements have not been evaluated by the FDA, SAHPRA, or other authorities. Always consult a licensed healthcare provider before use, especially if pregnant, breastfeeding, under 18, or managing medical conditions.